Apart from a brief mention in Bits and Bobs over 12 months ago, we don't seem to have mentioned this. It is, basically, Guitar Hero (just guitar, although bass is supposed to be coming in DLC), but with a real guitar, and in theory, the game can be played by anyone, regardless of whether or not you've actually touched a real guitar or not, as it's supposed to adapt to how well you can play songs, and expects you to get better over a long period, as opposed to throwing one song at you until you can play it perfectly. It also makes you learn the basics through a series of mini games.
The setlist ,as shamelessly copied from wikipedia, has got me interested
ZOMG Spoiler! Click here to view!
"House of the Rising Sun" The Animals 1964
"When I'm with You" Best Coast 2010
"I Got Mine" The Black Keys 2008
"Next Girl" The Black Keys 2010
"Song 2" Blur 1997
"Step Out of the Car" The Boxer Rebellion 2011
"Sunshine of Your Love" Cream 1967
"We Share the Same Skies" The Cribs 2009
"Boys Don't Cry" The Cure 1979
"I Want Some More" Dan Auerbach 2009
"Rebel Rebel" David Bowie 1974
"I Can't Hear You" The Dead Weather 2010
"Run Back to Your Side" Eric Clapton 2010
"Take Me Out" Franz Ferdinand 2004
"Do You Remember" The Horrors 2009
"I Miss You" Incubus 1999
"Slow Hands"[9] Interpol 2004
"Angela" Jarvis Cocker 2009
"Well OK Honey" Jenny O 2010
"Use Somebody" Kings of Leon 2008
"Are You Gonna Go My Way" Lenny Kravitz 1993
"Surf Hell" Little Barrie 2011
"Sweet Home Alabama" Lynyrd Skynyrd 1974
"Unnatural Selection" Muse 2009
"Plug In Baby" Muse 2001
"In Bloom" Nirvana 1991
"Breed" Nirvana 1991
"Where is My Mind?" Pixies 1988
"Go With the Flow" Queens of the Stone Age 2002
"High and Dry" Radiohead 1995
"California Brain" RapScallions 2011
"Number Thirteen" Red Fang 2011
"Higher Ground" Red Hot Chilli Peppers 1989
"(I Can't Get No) Satisfaction"[10] The Rolling Stones 1965
"The Spider and the Fly" The Rolling Stones 1965
"Play with Fire" The Rolling Stones 1965
"Gobbledigook" Sigur Rós 2008
"Panic Switch" Silversun Pickups 2009
"Outshined" Soundgarden 1991
"Me and the Bean" Spoon 2001
"Between the Lines" Stone Temple Pilots 2010
"Vasoline" Stone Temple Pilots 1994
"Under Cover of Darkness" The Strokes 2011
"Mean Bitch" Taddy Porter 2010
"A More Perfect Union" Titus Andronicus 2010
"Good Enough" Tom Petty and the Heartbreakers 2010
"Slither" Velvet Revolver 2004
"Burnished" White Denim 2011
"Icky Thump" The White Stripes 2007
"Islands" The xx 2009
"Chimney" The Yellow Moon Band 2009
as has the currently available DLC.
ZOMG Spoiler! Click here to view!
"Free Bird" Lynyrd Skynyrd 1973 Rock Hits 1 Nov. 1, 2011
"Bodysnatchers" Radiohead 2007 Rock Hits 1 Nov. 1, 2011
"Tighten Up" The Black Keys 2010 Rock Hits 1 Nov. 1, 2011
"Smoke on the Water" Deep Purple 1972 Rock Hits 70s Nov. 15, 2011
"More than a Feeling" Boston 1976 Rock Hits 70s Nov. 15, 2011
"Jessica" The Allman Brothers Band 1973 Rock Hits 70s Nov. 15, 2011
"Cousins" Vampire Weekend 2010 Rock Hits 2 Nov. 29, 2011
"20th Century Boy" T. Rex 1973 Rock Hits 2 Nov. 29, 2011
"I Hate Everything About You" Three Days Grace 2004 Rock Hits 2 Nov. 29, 2011
"Symphony of Destruction" Megadeth 1992 Megadeth Song Pack Dec. 13, 2011
"Hangar 18" Megadeth 1990 Megadeth Song Pack Dec. 13, 2011
"Public Enemy No. 1" Megadeth 2011 Megadeth Song Pack Dec. 13, 2011
"Carol of the Bells" Seth Chapla 2011 Holiday Song Pack Dec. 20, 2011
"God Rest Ye Merry, Gentlemen" Brian Adam McCune 2011 Holiday Song Pack Dec. 20, 2011
"We Three Kings" Versus Them 2011 Holiday Song Pack Dec. 20, 2011
“Just Got To Be” The Black Keys 2006 The Black Keys Song Pack Dec. 27, 2011
“Mind Eraser” The Black Keys 2011 The Black Keys Song Pack Dec. 27, 2011
“Gold On The Ceiling” The Black Keys 2011 The Black Keys Song Pack Dec. 27, 2011
"(Don't Fear) The Reaper” Blue Öyster Cult 1976 Rock Hits 60s-70s Jan. 17, 2012
"Space Oddity” David Bowie 1969 Rock Hits 60s-70s Jan. 17, 2012
"Barracuda” Heart 1977 Rock Hits 60s-70s Jan. 17, 2012
"Jeremy" Pearl Jam 1991 Pearl Jam Song Pack Feb. 7, 2012
"Black" Pearl Jam 1991 Pearl Jam Song Pack Feb. 7, 2012
"Dammit" Blink-182 1997 Blink-182 Song Pack Feb. 21, 2012
"All The Small Things" Blink-182 2000 Blink-182 Song Pack Feb. 21, 2012
"What's My Age Again?" Blink-182 1999 Blink-182 Song Pack Feb. 21, 2012
"Kryptonite" 3 Doors Down 2000 3 Doors Down Song Pack Mar. 6, 2012
"Loser" 3 Doors Down 2000 3 Doors Down Song Pack Mar. 6, 2012
"When I'm Gone" 3 Doors Down 2002 3 Doors Down Song Pack Mar. 6, 2012
"The Thrill is Gone" B.B. King 1969 Blues Hits Mar. 20, 2012
"Born Under a Bad Sign" Albert King with Stevie Ray Vaughan 1967 Blues Hits Mar. 20, 2012
"Soul Man" The Blues Brothers 1978 Blues Hits Mar. 20, 2012
"Bring Me to Life" Evanescence 2003 Rock Hits 3 Apr. 3, 2012
"Pumped Up Kicks" Foster the People 2011 Rock Hits 3 Apr. 3, 2012
"This Love" Maroon 5 2002 Rock Hits 3 Apr. 3, 2012
"Breaking the Law" Judas Priest 1980 Judas Priest Song Pack Apr. 17, 2012
"Living After Midnight" Judas Priest 1980 Judas Priest Song Pack Apr. 17, 2012
"Painkiller" Judas Priest 1990 Judas Priest Song Pack Apr. 17, 2012
As someone that seems to have lost interest in games in general recently, and has never picked up a non-plastic guitar, I'm interested enough in this to throw some money at it (it's not cheap, $80 in the US, because you need an adaptor, and that's assuming you've got access to a guitar), but unfortunately, there's the problem. The game has been out (on PS3 and 360) for about 6 months in North America, but currently the UK release date is sitting at October, nearly a full year after the original release (apparently, there's a band from Southend with the same name, and I heard something about some sort of patent issue, but I don't know which of those, if either, is the cause of the delay). The 360 version isn't region free, but the PS3 one is, although you'll have to use a US account to purchase the DLC.
I guess I'll have to see if the novelty has worn off in six months (assuming it does come out then).